Policies for biodefense revisited: The prioritized vaccination process for smallpox
نویسنده
چکیده
Handling bioterror events that involve contagious agents is a major concern in the war against terror, and is a cause for debate among policymakers about the best response policy. At the core of this debate stands the question which of the two post-event policies to adopt: mass vaccination—where maximum vaccination capacity is utilized to uniformly inoculate the entire population, or trace (also called ring or targeted) vaccination—where mass vaccination capabilities are traded off with tracing capabilities to selectively inoculate only contacts (or suspected contacts) of infective individuals. We present a dynamic epidemic-intervention model that expands previous models by capturing some additional key features of the situation and by generalizing some assumptions regarding the probability distributions of inter-temporal parameters. The model comprises a set of difference equations. The model is implemented to analyze alternative response policies. It is shown that a mixture of mass and trace vaccination policies—the prioritized vaccination policy—is more effective than either of the two aforementioned policies.
منابع مشابه
Hospital decision-making regarding the smallpox pre-event vaccination program.
OBJECTIVES To understand the factors underlying the decision by U.S. hospitals to participate or not in the U.S. Smallpox Pre-Event Vaccination Program (SPVP). METHODS We conducted semistructured telephone interviews with a convenience sample of 123 hospital decision-makers in nine states between June and November 2003. RESULTS Within our sample, 88 hospitals (72%) decided to participate in...
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ورودعنوان ژورنال:
- Annals OR
دوره 148 شماره
صفحات -
تاریخ انتشار 2006